CurQD® may support:
- Encouraging balanced activity within the intestinal environment
- Promoting a balanced gut environment
- Supports overall gut well-being
- Helps sooth intestinal discomfort
What is CurQD®?
CurQD® contains two herbal extracts in differing ratios which we tailor to meet the unique nutritional requirements of the individual:
- Cura: A gut-directed form of curcumin shown in placebo-controlled trials to exert a positive impact on markers of gut health (Lang et al, CGH 2015). Cura has been found to support healthy cytokine levels, support barrier function and positively alter the composition of the gut microbiome.
- QD1: An extract of Indigo plants found in clinical trials to maintain a healthy digestive system and support mucosal membranes (Naganuma et al, Gastroenterology 2018, Ben-Horin et al, CCFA 2023).Because QD1 is described in studies as having more rapid nutritional activity and Cura as having longer-term maintenance potential, the two are combined in specific ratios designed to align with different phases of use—from initial support to ongoing digestive balance.
After decades of inquiry into plant-derived compounds and their interaction with the intestinal environment, the CurQD® approach was developed as a tailored protocol for individuals.
In a 2022 retrospective study involving individuals with active intestinal imbalance, dosing adjustments were made based on participant progress. Researchers reported patterns of improvement in several measured indicators, noting that personalized adjustments appeared to influence overall outcomes.
Why It Stands Out
- Natural products
- Scientifically-backed dosage
- Adjusts to you and your changing needs.
If you’re looking for a way to support your gut health, then look no further than CurQD®: our natural protocol formulated specifically to help balance the microbiome.
Putting You First with Personalized Care.
The CurQD® Protocols use clinically-tested evidence to personalize protocols to your needs in the moment to promote gut health for a lifetime.
Each 6-week protocol includes natural compounds at specific ratios found to promote a healthy gut.
These protocols have been refined through years of research, real-world implementation and international clinical trials to ensure precision.
In protocols that require higher levels of support, QD1 may be initiated at elevated doses. Over time, dosing is tapered while Cura is increased to help maintain digestive balance and support overall gut health.
The Evidence
Learn more about the scientific publications related to CurQD® on our Science Page – including abstracts, study summaries, and reference links.
FAQ
What protocol should I take?
We normally recommend starting with the Green Protocol, which assists consumers in acclimating to the CurQD® combination. Afterwards, they will take a personalized protocol.
For more information, please email info@curqd.com.
How does it work?
Our natural formulations contain plant-derived molecules that engage a specific biological pathway associated with the aryl hydrocarbon receptor (AhR). When activated, this pathway has been described in scientific literature as helping support intestinal integrity and promoting balance within the gut environment.
The AhR pathway has become a growing area of interest in emerging research on gut-related biology. CurQD® is the first formulation shown in clinical studies to interact with this pathway in a way that supports gut balance and overall digestive well-being.
Why 6 weeks?
Our experience, and real-world data from gold-standard clinical trials, shows that you should see results after each 6-week protocol. Therefore, you’ll require a different protocol as you notice results. Each protocol slightly tapers down the fast-acting Qing Dai (QD1) and increases the ratio of the preventive, gut-directed curcumin (Cura).
In our recent clinical trials, we found this adjustment led to more positive results.
What are the daily doses?
Four capsules daily: two in the morning with food, two in the evening with food.
Can I take CurQD® long-term?
In our experience CurQD® products can be used for up to 6 months at a time. Ideally, your dose will gradually decrease within this period.
Maintenance protocols Blue+ and Blue have been used beyond this 6 month period. The Blue Protocol, containing only Cura, may be taken long-term.
Is CurQD® safe for children?
The Blue+ and Blue CurQD® Protocols are approved for use in children from ages 5 and above. The full CurQD® Protocol is approved for use in children ages 8 and above. Dosing is dependent on age and weight.
Please note that this information is general and not a substitute for professional guidance. We always encourage families to consult a healthcare provider before introducing any new supplement or routine.
What are the potential side effects of CurQD®?
Headaches – commonly experienced in the first 72 hours of treatment
Mild transient elevation of liver enzymes – blood tests are recommended 3-6 weeks after starting CurQD® (assessing ALT and AST)
Shortness of breath
Any unexplained symptom
Unfamiliar abdominal pain and/or severe diarrhea may be a sign of a rare delayed allergic reaction that may progress to intussusception/ischemic colitis. Please stop treatment immediately and contact info@curqd.com for next steps.
Qing Dai has on rare occasions been associated with pulmonary arterial hypertension (PAH) which dissipated upon discontinued use. Zero cases have been reported with CurQD®.
Why can’t I just use normal curcumin?
Most commercially available curcumin products have enhanced absorption (or high bioavailability) using different additives such as black pepper or a phospholipid complex. This mechanism is not suitable for supporting gut health as the active compounds lose concentration and potency before reaching the distal intestinal tract.
Cura is ‘gut-directed’, meaning it is specifically designed to reach high concentration in the gut so it can make direct contact with the intestinal lining of the digestive tract. It is the only curcumin product developed specifically for supporting gut health and was tested with great success in our clinical trials, as seen in a meta-analysis showing significantly higher efficacy rates for Cura compared to other forms of curcumin.
Is curcumin the same as turmeric?
No. Curcumin is the active compound; turmeric only contains ~2%. We use 95% concentration.
Will any Qing Dai formula work?
As far as we are aware, Evinature’s QD is one of the only Qing Dai extracts on the market that has been verified through LCMS-testing to contain measurable levels of its key plant constituents, including indigo and indirubin. Without this type of analytical confirmation, commercially available Qing Dai products may vary widely in composition.
CurQD® uses a specific ratio of its two botanical components, each studied for their interactions within the gut environment. These components play different roles within the formulation and are combined intentionally based on years of scientific inquiry into plant-derived compounds and how they behave in intestinal settings.
If you are using another form of Qing Dai, we do not recommend combining products unless advised by a healthcare professional.